Hi there. We have had a big 18kw ducted unit installed on our roof for more than 6 years now on a Polyslab and haven't had any issues. Originally we were concerned the Poly wouldn't stand up to the harsh QLD sun as it is right in the middle of our roof with no protection. I was up there the other day and no worries at all. Actually both our AC and our Hot Water System are installed on Polyslabs both on the roof.
The AC unit is screwed down to the Polyslab with stainless screws and some adhesive and they have placed a thin 8mm rubber pad between the unit and the Polyslab. The Polyslab is then screwed straight into the ribs of the metal roofing. We haven't had any noise issues at all and would highly recommend it.